See here for my Pubmed profile
Peer Reviewed:
Johnston I, Osborn LJ, Markley RL, McManus EA, Kadam A, Schultz KB, Nagajothi N, Ahern PP, Brown JM, Claesen J.
Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation.
NPJ Biofilms Microbiomes. 2021 Jul 2;7(1):56. doi: 10.1038/s41522-021-00226-3.
Wu M, Chen Y, Xia H, Wang C, Tan CY, Cai X, Liu Y, Ji F, Xiong P, Liu R, Guan Y, Duan Y, Kuang D, Xu S, Cai H, Xia Q, Yang D, Wang MW, Chiu IM, Cheng C, Ahern PP, Liu L, Wang G, Surana NK, Xia T, Kasper DL.
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases.
Proc. Natl. Acad. Sci., 2020 Oct 20:202018030, doi: 10.1073/pnas.2018030117
Di Luccia B*, Ahern PP*, Griffin NW*, Cheng J, Guruge JL, Byrne AE, Rodionov DA, Leyn SA, Osterman AL, Ahmed T, Colonna M, Barratt MJ, Delahaye NF, Gordon JI.
Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition.
Cell Host Microbe, 2020 Jun 10;27(6):899-908.e5, doi: 10.1016/j.chom.2020.04.008
*, equal contribution
Cowardin CA, Ahern PP, Kung VL, Hibberd MC, Cheng J, Guruge JL, Sundaresan V, Head RD,
Barile D, Mills DA, Barratt MJ, Huq S, Ahmed T, Gordon JI.
Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition.
Proc. Natl. Acad. Sci., 2019 Jun 11;116(24):11988-11996, doi: 10.1073/pnas.1821770116
Cervantes-Barragan L, Chai JN, Tianero MD, Di Luccia B, Ahern PP, Merriman J, Cortez VS, Caparon MG, Donia MS, Gilfillan S, Cella M, Gordon JI, Hsieh CS, Colonna M.
Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells.
Science, 2017 Aug 25; 357(6353): 806-810
Griffin NW, Ahern PP, Cheng J, Heath AC, Ilkayeva O, Newgard CB, Fontana L, Gordon JI.
Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions.
Cell Host Microbe., 2017 Jan 11;21(1):84-96
Semenkovich NP, Planer JD, Ahern PP, Griffin NW, Lin CY, Gordon JI.
Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes.
Proc. Natl. Acad. Sci., 2016 Dec 20;113(51):14805-14810.
Wagner VE, Dey N, Guruge J, Hsiao A, Ahern PP, Semenkovich NP, Blanton LV, Cheng J, Griffin N, Stappenbeck TS, Ilkayeva O, Newgard CB, Petri W, Haque R, Ahmed T, Gordon JI.
Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.
Sci. Transl. Med., 2016 Nov 23;8(366):366ra164.
Krausgruber T, Schiering C, Adelmann K, Harrison OJ, Chomka A, Pearson C, Ahern PP, Shale M, Oukka M, Powrie F.
T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine.
Nat Commun., 2016 May 19;7:11627
Rakoff-Nahoum S, Kong Y, Kleinstein SH, Subramanian S, Ahern PP, Gordon JI, Medzhitov R.
Analysis of gene-environment interactions in postnatal development of the mammalian intestine.
Proc Natl Acad Sci., 2015 Feb 17;112(7):1929-36
Faith JJ*, Ahern PP*, Ridaura VK, Cheng J, Gordon JI.
Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice.
Sci Transl Med., 2014 Jan 22;6(220):220ra11
*, equal contribution
Rey FE, Gonzalez MD, Cheng J, Wu M, Ahern PP, Gordon JI.
Metabolic niche of a prominent sulfate-reducing human gut bacterium.
Proc Natl Acad Sci., 2013 Aug 13; 110(33):13582-7
Yockey LJ, Demehri S, Turkoz M, Turkoz A, Ahern PP, Jassim O, Manivasagam, Kearney JF, Gordon JI, Kopan R.
The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation.
J Invest Dermatol., 2013 Epub May 22; 133(12):2714-21
Ahern PP*, Schiering C*, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity, 2010 Aug 27;33(2):279-88
*, equal contribution
Buonocore S, Ahern PP, Uhlig HH, Ivanov II, Littman DR, Maloy KJ and Powrie F.
Innate lymphoid cells drive interleukin-23 dependent innate intestinal pathology.
Nature, 2010 Apr 29;464(7293):1371-5
Izcue A, Hue S, Buonocore S, Arancibia-Cárcamo CV, Ahern PP, Iwakura Y, Maloy KJ and Powrie F.
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
Immunity, 2008 Apr;28(4):559-70
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F and Maloy KJ.
Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med., 2006 Oct 30;203(11):2473-83
Reviews:
Glowacki RWP, Engelhart MJ, Ahern PP#
Controlled Complexity: Optimized Systems to Study the Role of the Gut Microbiome in Host Physiology.
Front Microbiol. 2021 Sep 27;12:735562. doi: 10.3389/fmicb.2021.735562. eCollection 2021.
#, corresponding author
Ahern PP# and Maloy KJ.
Understanding immune-microbiota interactions in the intestine.
Immunology, 2020 Jan;159(1):4-14, doi: 10.1111/imm.13150.
#, corresponding author
Ahmed T, Auble D, Berkley JA, Black R, Ahern PP, Hossain M, Hsieh A, Ireen S, Arabi M, Gordon JI.
An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome.
Ann N Y Acad Sci., 2014 Aug 12, doi: 10.1111/nyas.12487
Ahern PP*, Faith JJ*, Gordon JI.
Mining the human gut microbiota for effector strains that shape the immune system.
Immunity, 2014 Jun 19;40(6):815-23
*, equal contribution
Kau AL*, Ahern PP*, Griffin NW, Goodman AL, Gordon JI.
Human nutrition, the gut microbiome and the immune system.
Nature, 2011 Jun 15; 474(7351):327-36
*, equal contribution
Ahern PP, Izcue A, Maloy KJ and Powrie F.
The interleukin-23 axis in Intestinal Inflammation.
Immunological Reviews, 2008, Dec;226;147-59
Peer Reviewed:
Johnston I, Osborn LJ, Markley RL, McManus EA, Kadam A, Schultz KB, Nagajothi N, Ahern PP, Brown JM, Claesen J.
Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation.
NPJ Biofilms Microbiomes. 2021 Jul 2;7(1):56. doi: 10.1038/s41522-021-00226-3.
Wu M, Chen Y, Xia H, Wang C, Tan CY, Cai X, Liu Y, Ji F, Xiong P, Liu R, Guan Y, Duan Y, Kuang D, Xu S, Cai H, Xia Q, Yang D, Wang MW, Chiu IM, Cheng C, Ahern PP, Liu L, Wang G, Surana NK, Xia T, Kasper DL.
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases.
Proc. Natl. Acad. Sci., 2020 Oct 20:202018030, doi: 10.1073/pnas.2018030117
Di Luccia B*, Ahern PP*, Griffin NW*, Cheng J, Guruge JL, Byrne AE, Rodionov DA, Leyn SA, Osterman AL, Ahmed T, Colonna M, Barratt MJ, Delahaye NF, Gordon JI.
Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition.
Cell Host Microbe, 2020 Jun 10;27(6):899-908.e5, doi: 10.1016/j.chom.2020.04.008
*, equal contribution
Cowardin CA, Ahern PP, Kung VL, Hibberd MC, Cheng J, Guruge JL, Sundaresan V, Head RD,
Barile D, Mills DA, Barratt MJ, Huq S, Ahmed T, Gordon JI.
Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition.
Proc. Natl. Acad. Sci., 2019 Jun 11;116(24):11988-11996, doi: 10.1073/pnas.1821770116
Cervantes-Barragan L, Chai JN, Tianero MD, Di Luccia B, Ahern PP, Merriman J, Cortez VS, Caparon MG, Donia MS, Gilfillan S, Cella M, Gordon JI, Hsieh CS, Colonna M.
Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells.
Science, 2017 Aug 25; 357(6353): 806-810
Griffin NW, Ahern PP, Cheng J, Heath AC, Ilkayeva O, Newgard CB, Fontana L, Gordon JI.
Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions.
Cell Host Microbe., 2017 Jan 11;21(1):84-96
Semenkovich NP, Planer JD, Ahern PP, Griffin NW, Lin CY, Gordon JI.
Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes.
Proc. Natl. Acad. Sci., 2016 Dec 20;113(51):14805-14810.
Wagner VE, Dey N, Guruge J, Hsiao A, Ahern PP, Semenkovich NP, Blanton LV, Cheng J, Griffin N, Stappenbeck TS, Ilkayeva O, Newgard CB, Petri W, Haque R, Ahmed T, Gordon JI.
Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.
Sci. Transl. Med., 2016 Nov 23;8(366):366ra164.
Krausgruber T, Schiering C, Adelmann K, Harrison OJ, Chomka A, Pearson C, Ahern PP, Shale M, Oukka M, Powrie F.
T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine.
Nat Commun., 2016 May 19;7:11627
Rakoff-Nahoum S, Kong Y, Kleinstein SH, Subramanian S, Ahern PP, Gordon JI, Medzhitov R.
Analysis of gene-environment interactions in postnatal development of the mammalian intestine.
Proc Natl Acad Sci., 2015 Feb 17;112(7):1929-36
Faith JJ*, Ahern PP*, Ridaura VK, Cheng J, Gordon JI.
Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice.
Sci Transl Med., 2014 Jan 22;6(220):220ra11
*, equal contribution
Rey FE, Gonzalez MD, Cheng J, Wu M, Ahern PP, Gordon JI.
Metabolic niche of a prominent sulfate-reducing human gut bacterium.
Proc Natl Acad Sci., 2013 Aug 13; 110(33):13582-7
Yockey LJ, Demehri S, Turkoz M, Turkoz A, Ahern PP, Jassim O, Manivasagam, Kearney JF, Gordon JI, Kopan R.
The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation.
J Invest Dermatol., 2013 Epub May 22; 133(12):2714-21
Ahern PP*, Schiering C*, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity, 2010 Aug 27;33(2):279-88
*, equal contribution
Buonocore S, Ahern PP, Uhlig HH, Ivanov II, Littman DR, Maloy KJ and Powrie F.
Innate lymphoid cells drive interleukin-23 dependent innate intestinal pathology.
Nature, 2010 Apr 29;464(7293):1371-5
Izcue A, Hue S, Buonocore S, Arancibia-Cárcamo CV, Ahern PP, Iwakura Y, Maloy KJ and Powrie F.
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
Immunity, 2008 Apr;28(4):559-70
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F and Maloy KJ.
Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med., 2006 Oct 30;203(11):2473-83
Reviews:
Glowacki RWP, Engelhart MJ, Ahern PP#
Controlled Complexity: Optimized Systems to Study the Role of the Gut Microbiome in Host Physiology.
Front Microbiol. 2021 Sep 27;12:735562. doi: 10.3389/fmicb.2021.735562. eCollection 2021.
#, corresponding author
Ahern PP# and Maloy KJ.
Understanding immune-microbiota interactions in the intestine.
Immunology, 2020 Jan;159(1):4-14, doi: 10.1111/imm.13150.
#, corresponding author
Ahmed T, Auble D, Berkley JA, Black R, Ahern PP, Hossain M, Hsieh A, Ireen S, Arabi M, Gordon JI.
An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome.
Ann N Y Acad Sci., 2014 Aug 12, doi: 10.1111/nyas.12487
Ahern PP*, Faith JJ*, Gordon JI.
Mining the human gut microbiota for effector strains that shape the immune system.
Immunity, 2014 Jun 19;40(6):815-23
*, equal contribution
Kau AL*, Ahern PP*, Griffin NW, Goodman AL, Gordon JI.
Human nutrition, the gut microbiome and the immune system.
Nature, 2011 Jun 15; 474(7351):327-36
*, equal contribution
Ahern PP, Izcue A, Maloy KJ and Powrie F.
The interleukin-23 axis in Intestinal Inflammation.
Immunological Reviews, 2008, Dec;226;147-59